تأثیر فعالیت ورزشی استقامتی برنشانگر قلبی و پاسخ ایمنی ناشی از ورزش در قایقرانان مرد نخبه

  Introduction : Biochemical and immunological investigations have indicated cardiac dysfunction and damage with changes in cardiac markers and inflammatory cytokines after endurance exercise.Therefore, there is a rational background to study the effect of cardiac pathophysiology during endurance exercise.This study was undertaken to determine the effect of endurance exercise on cardiac and inflammatory markers in elite kayakers.   Methods : Male professional kayakers with mean age of 22.5±3.24yr, mean weight 78.7±7.18 kg and mean height of 184± 4.357cm participated in a quasi-experimental study. Participants kayakied 8000 meters with 75-80% heart rate for 60 minutes. Blood samples were taken before, immediately and three hours after a prolonged endurance kayaking. Repeated measures followed independ t-test used for statistical analysis. SPSS v>16 was used for analysis.   Results : NT-proBNP levels significantly increased (24.05 vs 19.362 pg/ml) (p<0.001) .The plasma IL-6 insignificantly decreased in response to prolonged endurance kayaking (0.755 to 0.74 pg/ml)(p=0.91). There was no association between IL-6 and NT-proBNP levels after exercise.   Conclusion: Exercise-induced increase in NT-proBNP may represent physiologic reaction under special conditions and seems to have no significant pathological effect in the athletes . Decreased IL-6 plasma levels did not indicate myocardial damage. Based on thge results of this study endurance exercise does not effect the cardiac dysfunction and structural myocardial damage.